연구진

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연구진

제1그룹

조성윤

약리학교실 (PhD)

E-Mail

sungyuncho@korea.ac.kr

연구내용

세포신호 기반 RNA 대사 연구
5′UTR·RBP 매개 선택적 번역 연구
암·근감소증 치료표적 발굴 연구

대표논문

1. Cho SY, Endress J, He L#, and Blenis J#. (2025). Understand 5-fluorouracil resistance mechanism driven through GSK3 localization regulation by mTORC1 signaling. 2024. (Under revision)

2.Xu, K., Wang, Y., Wang, F., Guo, Y., Ren, Y., Low, V., Cho, S., Liu, Q., Qiu, Y., Li, X., et al. (2025). SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice. J Cachexia Sarcopenia Muscle 16, e13734. https://doi.org/10.1002/jcsm.13734.

3. Koundouros, N., Nagiec, M.J., Bullen, N., Noch, E.K., Burgos-Barragan, G., Li, Z., He, L., Cho, S., Parang, B., Leone, D., et al. (2025). Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling. Science 387, eadm9805. https://doi.org/10.1126/science.adm9805.

4. Kim, J.-S., Cho, S., Jeong, M.-Y., Rivera-Piza, A., Kim, Y., Wu, C., Yoon, Y.E., Lee, I., Choi, J.-W., Lee, H.L., et al. (2025). β-Ionone suppresses colorectal tumorigenesis by activating OR51E2, a potential tumor suppressor. Phytomedicine, 156599. https://doi.org/10.1016/j.phymed.2025.156599.

5.He, L*., Cho, S*., and Blenis, J. (2025). mTORC1, the maestro of cell metabolism and growth. Genes Dev 39, 109–131. https://doi.org/10.1101/gad.352084.124.

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