연구진

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연구진

제1그룹

김은희

생리학교실 (PhD)

E-Mail

eunheekim@korea.ac.kr

연구내용

알츠하이머병 병태기전에서 성상교세포의 역할 연구

대표논문

1.Vijaya Kumar DK, Mitchell, TA, Tailor, BA, Moir AP, Navalpur Shanmugam NK, Eimer WA, Ghofrani J, Choi SH, Su C, Rodriguez A, Kim E, Moir RD, Tanzi RE (2025). Human amylin is a potent antimicrobial peptide that exhibits antimicrobial synergism with the amyloid-β protein. Alzheimers Dement, 21(8):e70490

2.Kim E, Tanzi RE, Choi SH (2025) Therapeutic Potential of Exercise-Hormone Irisin in Alzheimer&aposs Disease. Neural Regen Res., 20(6):1555-1564

3.Kim E, Kim H, Jedrychowski MP, Bakiasi G, Park J, Kruskop J, Choi Y, Kwak SS, Quinti L, Kim DY, Wrann CD, Spiegelman BM, Tanzi RE¶ and Choi SH¶(2023) Irisin reduces amyloid-β deposition by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling. Neuron, 111, 1-15 (¶: co-corresponding authors).

4.Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, Kitchen RR, Caldarone BJ, Bettio L, Christie BR, Schmider AB, Soberman RJ, Besnard A, Jedrychowski MP, Kim H, Tu H, Kim E, Choi SH, Tanzi RE, Spiegelman BM, Wrann CD (2021) Exercise hormone irisin is a critical regulator of cognitive function. Nat Metab., 3(8):1058-1070

5.McAlpine CS, Park J, Griciuc A, Kim E, Choi S, Jorfi M, Vinegoni C, Iwamoto Y, Chan CT, Poller WC, Mindur JE, He S, Anzai A, Kahles F, Janssen H, Weissleder R, Nahrendorf M, Tanzi RE¶, Swirski FK¶ (2021) Astrocytic interleukin-3 programs microglia and limits Alzheimer&aposs disease. Nature, 595(7869):701-706

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