Kim, Hyeon Soo

Department of Anatomy (MD, PhD)

E-Mail

anatomykim@korea.ac.kr

Research content

• Original research on muscles
• Study of substances secreted from muscles
• Research on development of treatment for sarcopenia and proximal paralysis

Representative paper

1. Kang, Min Ju; Moon, Ji Wook; Lee, Jung Ok; Kim, Ji Hae; Jung, Eun Jeong; Kim, Su Jin; Oh, Joo Yeon; Wu, Sang Woo; Lee, Pu Reum; Park, Sun Hwa; Kim, Hyeon Soo.

Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a. Journal of cachexia, sarcopenia and muscle, 2021(10.1002/jcs m.12833).




2. Kwak, So-Young; Chung, InHyeok; Kang, Joon; Perakakis, Nikolaos; Yoo, Eun Hye; Lee, Juhee; Jung, Hun Taek; Mun, Bo-Ram; Choi, Won-Seok; Kim, Oh Yoen; Kim, Seolsong; Kim, Eun-Kyoung; Oh, Hannah; Mantzoros, Christos S.; Chung, Ji Hyung; Kim, Hyeon Soo; Shin, Min-Jeong.

Sex specific effect of ATPase inhibitory factor 1 on body weight: studies in high fat diet induced obese mice and genetic association studies in humans. Metabolism, 2020(105:154171).




3. Lee, Jung Ok; Kang, Min Ju; Byun, Won Seok; Kim, Shin Ae; Seo, Il Hyeok; Han, Jeong Ah; Moon, Ji Wook; Kim, Ji Hae; Kim, Su Jin; Lee, Eun Jung; Park, Serk In; Park, Sun Hwa; Kim, Hyeon Soo.

 Metformin overcomes resistance to cisplatin in triple-negative breast cancer(TNBC) cells by targeting RAD51. Breast cancer research, 2019 (21(1):115).




4. Kim, Nami; Kang, Mi Sun; Nam, Miso; Kim, Shin Ae; Hwang, Geum-Sook; Kim, Hyeon Soo.

Eicosapentaenoic Acid (EPA) Modulates Glucose Metabolism by Targeting AMP-Activated Protein Kinase(AMPK) Pathway. International journal of molecular sciences, 2019(20(19):4751).




5. Chung, InHyeok; Kim, Shin Ae; Kim, Seolsong; Lee, Jung Ok; Park, Clara Yongjoo; Lee, Juhee; Kang, Jun; Lee, Jin Young; Seo, Ilhyeok; Lee, Hye Jeong; Han, Jeong Ah; Kang, Min Ju; Lim, Eunice; Kim, Su Jin; Wu, Sang Woo; Oh, Joo Yeon; Chung, Ji Hyung; Kim, Eun-Kyoung; Kim, Hyeon Soo; Shin, Min-Jeong.

Biglycan reduces body weight by regulating food intake in mice and improves glucose metabolism through AMPK/AKT dual pathways in skeletal muscle. FASEB journal, 2021(35(8):e21794).